5WUU: Complex structure of the first bromodomain of BRD4 with an inhibitor that containing a 2H-chromen-2-one ring
Complex structure of the first bromodomain of BRD4 with an inhibitor that containing a 2H-chromen-2-one ring. Determined by x-ray diffraction at 1.724 Å resolution. Released 2017.
Composition
This structure contains 1,213 atoms across 1 protein chain. Molecular weight: 17.04 kDa.
Primary citation
Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.. Sun, Z., Zhang, H., Chen, Z. et al., Bioorg. Med. Chem. Lett. (2017).
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