6Q3Z: Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 16k
Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 16k. Determined by x-ray diffraction at 2 Å resolution. Released 2019.
Composition
This structure contains 2,448 atoms across 1 protein chain. Molecular weight: 31.7 kDa.
Primary citation
Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.. Watts, E., Heidenreich, D., Tucker, E. et al., J.Med.Chem. (2019).
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