Major histocompatibility complex, class I, A (HLA-A) is a 371-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A140T913.
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The mean pLDDT of this model is 84.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 72% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 16% |
What pLDDT means and how to read it
Cell membrane, Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6O53 | X-ray | 1.4 Å | A=25-298 |
| 6O4Z | X-ray | 1.5 Å | A=25-298 |
| 7QPJ | X-ray | 1.54 Å | C=25-300 |
| 6O51 | X-ray | 1.55 Å | A=25-298 |
| 6O4Y | X-ray | 1.58 Å | A=25-298 |
| 7MJ7 | X-ray | 1.6 Å | A=25-300 |
| 7P3D | X-ray | 1.67 Å | A=25-300 |
| 7MJ9 | X-ray | 1.75 Å | A=25-300 |
| 7MJ8 | X-ray | 1.79 Å | A=25-300 |
| 7SA2 | X-ray | 1.85 Å | A=25-302 |
| 7MKB | X-ray | 1.9 Å | A=25-298 |
| 7U21 | X-ray | 1.9 Å | A/D=25-299 |
| 7MJ6 | X-ray | 1.95 Å | A=25-300 |
| 7P3E | X-ray | 2.0 Å | A/D=25-300 |
| 6Z9V | X-ray | 2.01 Å | A/D=25-300 |
| 7N1A | X-ray | 2.06 Å | A/D=25-299 |
| 8TBW | X-ray | 2.08 Å | A/D=25-299 |
| 7Q9A | X-ray | 2.1 Å | A=25-300 |
| 7LG3 | X-ray | 2.3 Å | A=25-298 |
| 7N1E | X-ray | 2.3 Å | A=25-299 |
Showing 20 of 50 experimental structures (best resolution first).
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