DNA and RNA

DNA stores genetic information in a double helix, and RNA copies, carries and even catalyzes with it. This collection starts with classic B-DNA, Z-DNA and RNA helices, then shows how proteins read DNA sequences, how DNA is packed into nucleosomes, and how polymerases copy it. It also includes folded RNAs such as transfer RNA, ribozymes and riboswitches.

Open B-DNA dodecamer (Dickerson dodecamer) in 3D

26 structures

B-DNA dodecamer (Dickerson dodecamer)1BNA
The first crystal structure of a full turn of B-DNA.
B-DNA dodecamer with bound cisplatin5BNA
Cisplatin is a cancer drug that attacks DNA.
Z-DNA, a left-handed double helix1DCG
RNA double helix1RNA
Human telomeric DNA G-quadruplex1KF1
Yeast phenylalanine transfer RNA1EHZ
Nucleosome core particle at 1.9 Å1KX5
DNA wrapped around eight histone proteins, the basic unit of chromatin.
Nucleosome core particle1AOI
Zif268 zinc fingers bound to DNA1ZAA
Lambda repressor bound to operator DNA1LMB
Trp repressor bound to operator DNA1TRO
Lac repressor dimer bound to operator DNA1EFA
GCN4 leucine zipper bound to DNA1YSA
p53 tumor suppressor bound to DNA1TUP
GAL4 transcription factor bound to DNA1D66
TATA-binding protein bound to a TATA box1YTB
TFIIB, TBP and TATA box ternary complex1VOL
HhaI DNA methyltransferase with DNA3MHT
This enzyme flips its target base out of the double helix.
DNase I, an enzyme that cuts DNA3DNI
T7 DNA polymerase copying DNA1T7P
RNA polymerase II1I50
Part of the work recognized by the 2006 Nobel Prize in Chemistry (Roger Kornberg).
Human topoisomerase I bound to DNA1A36
Full-length hammerhead ribozyme3ZD5
Group I intron P4-P6 ribozyme domain1GID
Adenine riboswitch1Y26
Human spliceosome (pre-catalytic B complex)6AHD

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