A0A158RFT4: Complement inhibitor RaCI2

Complement inhibitor RaCI2 is a 98-residue protein from Rhipicephalus microplus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: A0A158RFT4.

Organism
Rhipicephalus microplus
Length
98 residues
Mean pLDDT
71.3
Model
AF-A0A158RFT4-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 71.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate10%
70 to 90Confident: backbone generally right49%
50 to 70Low: treat with caution27%
Below 50Very low: often disordered regions14%

What pLDDT means and how to read it

Function

Complement inhibitor (PubMed:27018802). Prevents complement-mediated C5 activation by binding to C5 (PubMed:27018802). Binds C5 at a different binding site than the other tick complement inhibitors OmCI and CirpT1, and the drug eculizumab (By similarity)

Subcellular location

Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
5HCDX-ray2.98 ÅD=22-98
5IECNMRA=22-88

More AlphaFold highlights

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