HLA class II histocompatibility antigen DR beta chain (HLA-DRB1) is a 266-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A1V1IGJ9.
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The mean pLDDT of this model is 84.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 66% |
| 70 to 90 | Confident: backbone generally right | 10% |
| 50 to 70 | Low: treat with caution | 18% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Endosome membrane, Lysosome membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7YXB | X-ray | 2.1 Å | B/D=31-227 |
| 7O00 | X-ray | 2.24 Å | BBB=31-219 |
| 9NIH | X-ray | 2.4 Å | B=30-219 |
| 9B7B | X-ray | 3.08 Å | B/F=29-219 |
| 8EUQ | X-ray | 3.09 Å | B/G=30-219 |
| 9NIG | X-ray | 3.2 Å | B/D/I=31-220 |
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