Troponin I, cardiac muscle (TNNI3) is a 211-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 31 Mar 2025. UniProt accession: A0A4X1V520.
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The mean pLDDT of this model is 75.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 43% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 44% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8UWW | EM | 5.1 Å | D=1-211 |
| 8V0K | EM | 5.2 Å | D=1-211 |
| 8UYD | EM | 5.3 Å | D=1-211 |
| 8UZY | EM | 5.3 Å | D=1-211 |
| 8UZX | EM | 5.4 Å | D=1-211 |
| 8UWY | EM | 5.5 Å | D=1-211 |
| 8V01 | EM | 5.5 Å | D=1-211 |
| 8V0I | EM | 5.8 Å | D=1-211 |
| 8UZ5 | EM | 5.9 Å | D=1-211 |
| 8UWX | EM | 6.0 Å | D=1-211 |
| 8V0Y | EM | 7.0 Å | D=1-211 |
| 8UZ6 | EM | 7.1 Å | D=1-211 |
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