Troponin T, cardiac muscle (TNNT2) is a 285-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A5G2Q8N0.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 72.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 38% |
| 70 to 90 | Confident: backbone generally right | 19% |
| 50 to 70 | Low: treat with caution | 26% |
| Below 50 | Very low: often disordered regions | 17% |
What pLDDT means and how to read it
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8UWW | EM | 5.1 Å | E=1-285 |
| 8V0K | EM | 5.2 Å | E=1-285 |
| 8UYD | EM | 5.3 Å | E=1-285 |
| 8UZY | EM | 5.3 Å | E=1-285 |
| 8UZX | EM | 5.4 Å | E=1-285 |
| 8UWY | EM | 5.5 Å | E=1-285 |
| 8V01 | EM | 5.5 Å | E=1-285 |
| 8V0I | EM | 5.8 Å | E=1-285 |
| 8UZ5 | EM | 5.9 Å | E=1-285 |
| 8UWX | EM | 6.0 Å | E=1-285 |
| 8V0Y | EM | 7.0 Å | E=1-285 |
| 8UZ6 | EM | 7.1 Å | E=1-285 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.