MHC class I antigen (HLA-A) is a 367-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A5H2UYS3.
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The mean pLDDT of this model is 85.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 73% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 15% |
What pLDDT means and how to read it
Cell membrane, Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7JYV | X-ray | 1.51 Å | A=27-304 |
| 7MJA | X-ray | 1.69 Å | A=27-306 |
| 7EJM | X-ray | 1.71 Å | A=27-300 |
| 8SBK | X-ray | 1.8 Å | A=27-306 |
| 7EJL | X-ray | 1.89 Å | A=27-300 |
| 7WT3 | X-ray | 1.89 Å | A/D=26-302 |
| 7WT4 | X-ray | 1.89 Å | A/D=26-302 |
| 7K81 | X-ray | 2.0 Å | A=27-302 |
| 7EJN | X-ray | 2.11 Å | A=27-300 |
| 6XQA | X-ray | 2.16 Å | A/D=27-304 |
| 7NME | X-ray | 2.2 Å | A=27-302 |
| 7NMD | X-ray | 2.25 Å | A/D=27-302 |
| 7K80 | X-ray | 2.4 Å | A/D=27-302 |
| 7NMG | X-ray | 2.48 Å | A=27-302 |
| 7JYU | X-ray | 2.75 Å | A/D=27-304 |
| 7JYW | X-ray | 2.9 Å | A=27-304 |
| 7JYX | X-ray | 2.95 Å | A/D=27-304 |
| 7NMF | X-ray | 2.98 Å | A=27-302 |
| 8SBL | X-ray | 3.0 Å | A/D/G/J=27-306 |
| 8RJ5 | X-ray | 3.02 Å | A/F=27-302 |
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