Tubulin beta chain (TUBB2B) is a 445-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 31 Mar 2025. UniProt accession: A0A8D1UIR5.
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The mean pLDDT of this model is 86.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 49% |
| 70 to 90 | Confident: backbone generally right | 44% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13…
Cytoplasm, cytoskeleton
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8YUA | X-ray | 2.37 Å | B/D=1-431 |
| 9MLF | X-ray | 2.4 Å | B/D=1-433 |
| 9O6I | X-ray | 2.51 Å | B/D=1-433 |
| 8YTX | X-ray | 2.53 Å | B/D=1-431 |
| 9LNW | X-ray | 2.55 Å | B/D=1-445 |
| 9LNX | X-ray | 2.59 Å | B/D=1-445 |
| 8WD0 | X-ray | 2.6 Å | B/D=1-445 |
| 9LNV | X-ray | 2.67 Å | B/D=1-445 |
| 8UTS | EM | 2.7 Å | B=1-445 |
| 8WMU | X-ray | 2.7 Å | B/D=1-431 |
| 8YER | X-ray | 2.71 Å | B/D=1-431 |
| 8YEM | X-ray | 2.74 Å | B/D=1-431 |
| 8YRK | X-ray | 2.74 Å | B/D=1-445 |
| 8WMO | X-ray | 2.89 Å | B/D=1-445 |
| 8ZB8 | X-ray | 2.94 Å | B/D=1-445 |
| 9YA5 | EM | 2.95 Å | B/I=1-445 |
| 8UTU | EM | 3.0 Å | B=1-445 |
| 8UTV | EM | 3.0 Å | B=1-445 |
| 8YEU | X-ray | 3.05 Å | B/D=1-431 |
| 8F1A | EM | 3.1 Å | B=1-445 |
Showing 20 of 33 experimental structures (best resolution first).
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