A0A8V8TQW4: AP-3 complex subunit delta (AP3D1)

AP-3 complex subunit delta (AP3D1) is a 1203-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 31 Mar 2025. UniProt accession: A0A8V8TQW4.

Gene
AP3D1
Organism
Homo sapiens
Length
1203 residues
Mean pLDDT
71.3
Model
AF-A0A8V8TQW4-F1 v6
Model created
31 Mar 2025

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Model confidence (pLDDT)

The mean pLDDT of this model is 71.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate28%
70 to 90Confident: backbone generally right37%
50 to 70Low: treat with caution9%
Below 50Very low: often disordered regions25%

What pLDDT means and how to read it

Function

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals

Subunit structure

Adaptor protein complex 3 (AP-3) is a heterotetramer

Subcellular location

Cytoplasm, Golgi apparatus membrane

Experimental structures

UniProt lists no experimental PDB structure for this protein, so the AlphaFold prediction is the main 3D model available.

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.