MHC class I antigen (HLA-A) is a 328-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A5I8L1.
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The mean pLDDT of this model is 90.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 81% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
Cell membrane, Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9SKO | X-ray | 1.49 Å | A=9-283 |
| 9SL0 | X-ray | 1.6 Å | A=9-283 |
| 9SKP | X-ray | 1.89 Å | A=9-283 |
| 9NMV | X-ray | 1.97 Å | A=9-286 |
| 9NMY | X-ray | 2.01 Å | A=9-286 |
| 9NMU | X-ray | 2.1 Å | A=9-286 |
| 9NMW | X-ray | 2.11 Å | A=9-286 |
| 9NMX | X-ray | 2.19 Å | A=9-286 |
| 9O5S | X-ray | 2.27 Å | A/C/H/L=9-286 |
| 9YTD | EM | 2.5 Å | A=9-286 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.