Transcription factor TFIIIB component B'' homolog (BDP1) is a 2624-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: A6H8Y1.
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The mean pLDDT of this model is 37.0 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 2% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 92% |
What pLDDT means and how to read it
General activator of RNA polymerase III transcription. Requires for transcription from all three types of polymerase III promoters. Requires for transcription of genes with internal promoter elements and with promoter elements upstream of the initiation site
Component of TFIIIB complex. The TFIIIB complex has two activities, alpha and beta. The TFIIIB-alpha and TFIIIB-beta activities are required for transcription of genes with TFIIIC-bound internal promoters and PSE transcription factor-bound external promoters, respectively. The TFIIIB-alpha activity complex is composed of TBP, BDP1, and a complex containing both BRF2 and at least four stably…
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5N9G | X-ray | 2.7 Å | C/H=241-396 |
| 9K3U | EM | 3.0 Å | W=1-2624 |
| 9FSO | EM | 3.28 Å | T=1-484 |
| 9LXN | EM | 3.3 Å | W=1-2624 |
| 9FSP | EM | 3.39 Å | T=1-484 |
| 8IUH | EM | 3.4 Å | W=1-2624 |
| 9K3V | EM | 3.5 Å | W=1-2624 |
| 9FSQ | EM | 3.51 Å | T=1-484 |
| 9FSR | EM | 3.76 Å | T=1-484 |
| 8ITY | EM | 3.9 Å | W=1-2624 |
| 8IUE | EM | 4.1 Å | W=1-2624 |
| 9FSS | EM | 4.14 Å | T=1-484 |
| 9K3B | EM | 4.8 Å | W=1-2624 |
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