A6QIG7: Chemotaxis inhibitory protein (chp)

Chemotaxis inhibitory protein (chp) is a 149-residue protein from Staphylococcus aureus (strain Newman). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: A6QIG7.

Gene
chp
Organism
Staphylococcus aureus (strain Newman)
Length
149 residues
Mean pLDDT
74.3
Model
AF-A6QIG7-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 74.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate40%
70 to 90Confident: backbone generally right23%
50 to 70Low: treat with caution14%
Below 50Very low: often disordered regions24%

What pLDDT means and how to read it

Function

Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium

Subcellular location

Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
1XEENMRA=59-149
2K3UNMRA=59-149

More AlphaFold highlights

About this viewer

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