V-type proton ATPase catalytic subunit A (SCRG_00677) is a 617-residue protein from Saccharomyces cerevisiae (strain RM11-1a). This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: B3LH69.
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The mean pLDDT of this model is 89.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 66% |
| 70 to 90 | Confident: backbone generally right | 30% |
| 50 to 70 | Low: treat with caution | 2% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1)
Vacuole membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7TMS | EM | 3.8 Å | A/C/E=1-617 |
| 7TMT | EM | 3.8 Å | A/C/E=1-617 |
| 6O7V | EM | 6.6 Å | A/C/E=1-617 |
| 6O7W | EM | 7.0 Å | A/C/E=1-617 |
| 6O7X | EM | 8.7 Å | A/C/E=1-617 |
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