Histone H2B is a 166-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: B4DR52.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 73.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 51% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 20% |
| Below 50 | Very low: often disordered regions | 25% |
What pLDDT means and how to read it
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Chromosome, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7QXA | EM | 3.2 Å | M=1-166 |
| 9SHZ | EM | 3.2 Å | M=1-166 |
| 9QAX | EM | 3.3 Å | M=1-166 |
| 9SHY | EM | 3.53 Å | M=1-166 |
| 9QAZ | EM | 3.6 Å | M=1-166 |
| 7BG9 | EM | 3.8 Å | M=1-166 |
| 9QAY | EM | 3.8 Å | M=1-166 |
| 9SI0 | EM | 3.8 Å | M=1-166 |
| 7QXB | EM | 3.9 Å | M=1-166 |
| 7QXS | EM | 3.9 Å | M=1-166 |
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