Non-toxic nonhemagglutinin type A (ntnh) is a 1159-residue protein from Clostridium botulinum (strain Kyoto / Type A2). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: C1FUH8.
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The mean pLDDT of this model is 94.0 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 88% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Part of a botulinum neurotoxin type A2 (BoNT) locus; may be part of a progenitor toxin complex required to protect BoNT during its passage through the host gastrointestinal tract
Part of a crude toxin extract that includes BoNTA2/NTNH, P47, OrfX2 and OrfX3; OrfX1 was not detected. A purified toxin complex has NTNH and dichain BoNTA2 (PubMed:19915042). Forms a highly interlocked heterodimer with botulinum neurotoxin type A2 at pH 6.0, called the minimally functional progenitor toxin complex (M-PTC) (BoNT/A, botA) (PubMed:29067689)
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9ARL | EM | 4.0 Å | B=1-1159 |
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