HLA class II histocompatibility antigen DR beta chain (HLA-DRB1) is a 266-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: D7RIG0.
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The mean pLDDT of this model is 84.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 66% |
| 70 to 90 | Confident: backbone generally right | 10% |
| 50 to 70 | Low: treat with caution | 18% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Endosome membrane, Lysosome membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8CMC | X-ray | 1.42 Å | B=30-219 |
| 8CMG | X-ray | 1.64 Å | B=30-219 |
| 8CMH | X-ray | 1.64 Å | B=30-219 |
| 8CMB | X-ray | 1.84 Å | B=30-219 |
| 8CMF | X-ray | 2.2 Å | B/E=30-219 |
| 8CME | X-ray | 2.26 Å | B/E/H=30-219 |
| 8VSJ | EM | 2.28 Å | B=30-219 |
| 8CMD | X-ray | 2.54 Å | B/E/H=30-219 |
| 8CMI | X-ray | 2.6 Å | B/E/H=30-219 |
| 9BF9 | X-ray | 3.4 Å | B=29-227 |
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