Sorting nexin-3 (CTHT_0011560) is a 195-residue protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719). This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: G0S0X3.
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The mean pLDDT of this model is 76.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 52% |
| 70 to 90 | Confident: backbone generally right | 14% |
| 50 to 70 | Low: treat with caution | 11% |
| Below 50 | Very low: often disordered regions | 24% |
What pLDDT means and how to read it
Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3))
Cytoplasm, Golgi apparatus membrane, Prevacuolar compartment membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7BLQ | EM | 9.2 Å | G/L=71-186 |
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