O14241: Actin-related protein 2/3 complex subunit 2 (arc2)

Actin-related protein 2/3 complex subunit 2 (arc2) is a 317-residue protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O14241.

Gene
arc2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
317 residues
Mean pLDDT
92.8
Model
AF-O14241-F1 v6
Model created
1 Aug 2025
PDB structures
6

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 92.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate88%
70 to 90Confident: backbone generally right7%
50 to 70Low: treat with caution5%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity)

Subunit structure

Component of the Arp2/3 complex composed of arp2, act2, arc1/p41-ARC, arc2/p34-ARC, arc3/p21-ARC, arc4/p20-ARC and arc5/p16-ARC

Subcellular location

Cytoplasm, cytoskeleton, actin patch

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8UXWEM2.7 ÅD=1-317
8UXXEM3.2 ÅD=1-317
8E9BEM3.5 ÅD=1-317
3DWLX-ray3.78 ÅD/I=1-317
6W17EM3.9 ÅD=1-317
6W18EM4.2 ÅD=1-317

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.