Multiprotein-bridging factor 1 (MBF1) is a 151-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O14467.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 79.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 34% |
| 70 to 90 | Confident: backbone generally right | 40% |
| 50 to 70 | Low: treat with caution | 19% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters (PubMed:9710580). Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation (PubMed:30465652, PubMed:36583309). Required to prevent stalled ribosomes from frameshifting (PubMed:30465652, PubMed:36583309)
Interacts with TBP and the transcription factor GCN4 (PubMed:9710580). Interacts with RPS3/us3 (PubMed:36583309)
Cytoplasm, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9F9S | EM | 2.9 Å | CN=1-151 |
| 6ZVI | EM | 3.0 Å | T=27-137 |
| 7NRD | EM | 4.36 Å | Sh=26-145 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.