O14669: Transmembrane gamma-carboxyglutamic acid protein 2 (PRRG2)

Transmembrane gamma-carboxyglutamic acid protein 2 (PRRG2) is a 202-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O14669.

Gene
PRRG2
Organism
Homo sapiens
Length
202 residues
Mean pLDDT
72.1
Model
AF-O14669-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 72.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate26%
70 to 90Confident: backbone generally right30%
50 to 70Low: treat with caution27%
Below 50Very low: often disordered regions17%

What pLDDT means and how to read it

Function

Vitamin K-dependent protein that is essential for calcium homeostasis and haemostasis

Subunit structure

Interacts with NEDD4 (By similarity). Interacts (via cytoplasmic domain) with transcriptional coactivator YAP1 (PubMed:17502622)

Subcellular location

Cell membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9BVPEM3.3 ÅP=24-139
9BVQEM3.3 ÅP=24-139

More AlphaFold highlights

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