O15498: Synaptobrevin homolog YKT6 (YKT6)

Synaptobrevin homolog YKT6 (YKT6) is a 198-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O15498.

Gene
YKT6
Organism
Homo sapiens
Length
198 residues
Mean pLDDT
90.9
Model
AF-O15498-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 90.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate79%
70 to 90Confident: backbone generally right15%
50 to 70Low: treat with caution4%
Below 50Very low: often disordered regions3%

What pLDDT means and how to read it

Function

Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment (PubMed:9211930, PubMed:15215310). Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5 (By similarity). Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5 (PubMed:15215310). Has a S-palmitoyl transferase activity (PubMed:15479160, PubMed:15044687). Essential for the structural and functional organization of the Golgi apparatus (PubMed:32128853)

Subunit structure

Identified in 2 different SNARE complexes; the first one composed of GOSR1, GOSR2 and STX5 and the second one composed of BET1L, GOSR1 and STX5

Subcellular location

Cytoplasm, cytosol, Cytoplasmic vesicle membrane, Golgi apparatus membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6J7XX-ray2.75 ÅC=1-198
6J7FX-ray2.88 ÅC=1-195
6J74X-ray3.21 ÅC=1-198

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