NAD-dependent protein deacylase 1 (cobB1) is a 245-residue protein from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O28597.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 96.2 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 90% |
| 70 to 90 | Confident: backbone generally right | 10% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1M2K | X-ray | 1.47 Å | A=1-245 |
| 1M2G | X-ray | 1.7 Å | A=1-245 |
| 1M2J | X-ray | 1.7 Å | A=1-245 |
| 4TWI | X-ray | 1.79 Å | A=1-245 |
| 1M2H | X-ray | 1.8 Å | A=1-245 |
| 1ICI | X-ray | 2.1 Å | A/B=1-245 |
| 1M2N | X-ray | 2.6 Å | A/B=1-245 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.