O43312: Protein MTSS 1 (MTSS1)

Protein MTSS 1 (MTSS1) is a 755-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O43312.

Gene
MTSS1
Organism
Homo sapiens
Length
755 residues
Mean pLDDT
61.6
Model
AF-O43312-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 61.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate31%
70 to 90Confident: backbone generally right4%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions54%

What pLDDT means and how to read it

Function

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton

Subunit structure

Binds to actin. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta

Subcellular location

Cytoplasm, cytoskeleton

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2D1KX-ray2.5 ÅC=724-755

More AlphaFold highlights

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