O43493: Trans-Golgi network integral membrane protein 2 (TGOLN2)

Trans-Golgi network integral membrane protein 2 (TGOLN2) is a 437-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O43493.

Gene
TGOLN2
Organism
Homo sapiens
Length
437 residues
Mean pLDDT
49.2
Model
AF-O43493-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 49.2 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate2%
70 to 90Confident: backbone generally right6%
50 to 70Low: treat with caution24%
Below 50Very low: often disordered regions68%

What pLDDT means and how to read it

Function

May be involved in regulating membrane traffic to and from trans-Golgi network

Subcellular location

Cell membrane, Golgi apparatus, trans-Golgi network membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6YAFEM9.1 ÅP=420-434

More AlphaFold highlights

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