O43927: C-X-C motif chemokine 13 (CXCL13)

C-X-C motif chemokine 13 (CXCL13) is a 109-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O43927.

Gene
CXCL13
Organism
Homo sapiens
Length
109 residues
Mean pLDDT
83.9
Model
AF-O43927-F1 v6
Model created
1 Aug 2025
PDB structures
4

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Model confidence (pLDDT)

The mean pLDDT of this model is 83.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate50%
70 to 90Confident: backbone generally right29%
50 to 70Low: treat with caution21%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5

Subcellular location

Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7JNYX-ray1.88 ÅA=23-109
5CBEX-ray2.4 ÅE/F=23-109
5CBAX-ray2.5 ÅE/F=23-109
6VGJX-ray2.52 ÅA/B/C/D/E/F/G=24-109

More AlphaFold highlights

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