O75616: GTPase Era, mitochondrial (ERAL1)

GTPase Era, mitochondrial (ERAL1) is a 437-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O75616.

Gene
ERAL1
Organism
Homo sapiens
Length
437 residues
Mean pLDDT
77.9
Model
AF-O75616-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 77.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate59%
70 to 90Confident: backbone generally right14%
50 to 70Low: treat with caution2%
Below 50Very low: often disordered regions24%

What pLDDT means and how to read it

Function

Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly

Subcellular location

Mitochondrion matrix, Mitochondrion inner membrane

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8CSQEM2.54 Åa=1-437
8CSPEM2.66 Åa=1-437

More AlphaFold highlights

About this viewer

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