Tsetse thrombin inhibitor (TTI) is a 53-residue protein from Glossina morsitans morsitans. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O97373.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 68.0 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 21% |
| 70 to 90 | Confident: backbone generally right | 15% |
| 50 to 70 | Low: treat with caution | 59% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Potent and specific inhibitor of human thrombin. It is also a potent inhibitor of thrombin-induced platelet aggregation. It is capable of antagonizing host hemostasis and facilitating blood feeding
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6TKL | X-ray | 1.3 Å | I=1-53 |
| 6TKG | X-ray | 1.35 Å | I=1-53 |
| 6TKI | X-ray | 1.8 Å | I=1-53 |
| 7PHX | X-ray | 1.8 Å | I=22-53 |
| 6TKH | X-ray | 1.9 Å | I=1-53 |
| 6TKJ | X-ray | 2.81 Å | I=1-53 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.