Triosephosphate isomerase (TPI1) is a 248-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P00942.
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The mean pLDDT of this model is 97.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 95% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Homodimer
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1NEY | X-ray | 1.2 Å | A/B=2-248 |
| 1NF0 | X-ray | 1.6 Å | A/B=2-248 |
| 1I45 | X-ray | 1.8 Å | A/B=2-248 |
| 4FF7 | X-ray | 1.86 Å | A/B=1-248 |
| 1YPI | X-ray | 1.9 Å | A/B=2-248 |
| 7TIM | X-ray | 1.9 Å | A/B=2-248 |
| 2YPI | X-ray | 2.5 Å | A/B=2-248 |
| 3YPI | X-ray | 2.8 Å | A/B=2-248 |
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