P01222: Thyrotropin subunit beta (TSHB)

Thyrotropin subunit beta (TSHB) is a 138-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P01222.

Gene
TSHB
Organism
Homo sapiens
Length
138 residues
Mean pLDDT
86.0
Model
AF-P01222-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 86.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate58%
70 to 90Confident: backbone generally right30%
50 to 70Low: treat with caution9%
Below 50Very low: often disordered regions3%

What pLDDT means and how to read it

Function

Indispensable for the control of thyroid structure and metabolism

Subunit structure

Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin

Subcellular location

Secreted

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7UTZEM2.4 ÅB=21-132
7T9IEM2.9 ÅB=21-132
7XW5EM2.96 ÅY=21-138

More AlphaFold highlights

About this viewer

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