Serum amyloid P-component (APCS) is a 223-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P02743.
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The mean pLDDT of this model is 94.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 91% |
| 70 to 90 | Confident: backbone generally right | 1% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin
Homopentamer. Pentraxin (or pentaxin) have a discoid arrangement of 5 non-covalently bound subunits
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4AVS | X-ray | 1.4 Å | A/B/C/D/E=20-223 |
| 3KQR | X-ray | 1.5 Å | A/B/C/D/E=20-223 |
| 4AYU | X-ray | 1.5 Å | A/B/C/D/E=20-223 |
| 4AVV | X-ray | 1.6 Å | A/B/C/D/E=20-223 |
| 2W08 | X-ray | 1.7 Å | A/B/C/D/E=20-223 |
| 1SAC | X-ray | 2.0 Å | A/B/C/D/E=20-223 |
| 2A3Y | X-ray | 2.0 Å | A/B/C/D/E=20-223 |
| 1GYK | X-ray | 2.2 Å | A/B/C/D/E=20-223 |
| 2A3W | X-ray | 2.2 Å | A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T=20-223 |
| 1LGN | X-ray | 2.8 Å | A/B/C/D/E=20-223 |
| 3D5O | X-ray | 2.8 Å | A/B/C/D/E=20-223 |
| 2A3X | X-ray | 3.0 Å | A/B/C/D/E/F/G/H/I/J=20-223 |
| 4AVT | X-ray | 3.2 Å | A/B/C/D/E/F/G/H/I/J=20-223 |
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