P06126: T-cell surface glycoprotein CD1a (CD1A)

T-cell surface glycoprotein CD1a (CD1A) is a 327-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P06126.

Gene
CD1A
Organism
Homo sapiens
Length
327 residues
Mean pLDDT
88.6
Model
AF-P06126-F1 v6
Model created
1 Aug 2025
PDB structures
16

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Model confidence (pLDDT)

The mean pLDDT of this model is 88.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate76%
70 to 90Confident: backbone generally right14%
50 to 70Low: treat with caution3%
Below 50Very low: often disordered regions6%

What pLDDT means and how to read it

Function

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells

Subunit structure

Heterodimer with B2M (beta-2-microglobulin). Interacts with CD74

Subcellular location

Cell membrane, Membrane raft, Endosome membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
5J1AX-ray1.86 ÅA=1-295
4X6FX-ray1.91 ÅA=21-295
7SH4X-ray2.0 ÅA=18-295
7KP1X-ray2.02 ÅA=18-295
4X6EX-ray2.1 ÅA=21-295
9OHZX-ray2.14 ÅA=20-295
1ONQX-ray2.15 ÅA/C=18-294
6NUXX-ray2.2 ÅA=21-295
7KOZX-ray2.25 ÅA=18-295
7KP0X-ray2.4 ÅA=18-295
7RYNX-ray2.7 ÅA=18-295
1XZ0X-ray2.8 ÅA/C=18-294
4X6CX-ray2.8 ÅA/C=21-295
4X6DX-ray2.98 ÅA/C=21-295
7RYOX-ray3.0 ÅA=18-295
7RYMX-ray3.2 ÅA=18-295

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