Vitamin B12 import system permease protein BtuC (btuC) is a 326-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P06609.
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The mean pLDDT of this model is 92.2 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 76% |
| 70 to 90 | Confident: backbone generally right | 22% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane
The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF)
Cell inner membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2QI9 | X-ray | 2.6 Å | A/B=1-326 |
| 4R9U | X-ray | 2.78 Å | A/B=1-326 |
| 1L7V | X-ray | 3.2 Å | A/B=1-326 |
| 4FI3 | X-ray | 3.47 Å | A/B=1-326 |
| 4DBL | X-ray | 3.49 Å | A/B/F/G=1-326 |
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