Enterotoxin type C-3 (entC3) is a 266-residue protein from Staphylococcus aureus (strain Mu50 / ATCC 700699). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0A0L3.
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The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 80% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of pro-inflammatory cytokines (By similarity). Also causes the intoxication staphylococcal food poisoning syndrome (By similarity)
Interacts with MHC class II molecules composed of alpha/HLA-DRA and beta/HLA-DRB1 chains. Interacts with host T-cell receptor/TCR beta variable chain TRBV8-2
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1PYW | X-ray | 2.1 Å | D=28-266 |
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