3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (fabA) is a 172-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0A6Q3.
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The mean pLDDT of this model is 97.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 95% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Necessary for the introduction of cis unsaturation into fatty acids (PubMed:8910376). Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to (2E)-decenoyl-ACP and then its isomerization to (3Z)-decenoyl-ACP (PubMed:8910376). Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (PubMed:10629181, PubMed:7592873, PubMed:8910376). Is inactive in the dehydration of long chain unsaturated beta-hydroxyacyl-ACP (PubMed:8910376)
Homodimer
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4KEH | X-ray | 1.9 Å | A/B=2-172 |
| 1MKA | X-ray | 2.0 Å | A/B=2-172 |
| 1MKB | X-ray | 2.0 Å | A/B=2-172 |
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