Large ribosomal subunit protein uL1 (rplA) is a 234-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0A7L0.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 81.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 3% |
| 70 to 90 | Confident: backbone generally right | 93% |
| 50 to 70 | Low: treat with caution | 2% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
One of the primary rRNA binding proteins, it binds very close to the 3'-end of the 23S rRNA. Forms part of the L1 stalk. It is often not seen in high-resolution crystal structures, but can be seen in cryo_EM and 3D reconstruction models. These indicate that the distal end of the stalk moves by approximately 20 angstroms (PubMed:12859903, PubMed:16272117). This stalk movement is thought to be coupled to movement of deacylated tRNA into and out of the E site, and thus to participate in tRNA translocation (PubMed:12859903, PubMed:16272117). Contacts the P and E site tRNAs
Part of the 50S ribosomal subunit. Cross-links to the P and E site tRNAs
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9SLG | EM | 2.16 Å | 6=1-234 |
| 7UG7 | EM | 2.58 Å | LA=1-234 |
| 9SS6 | EM | 2.6 Å | BA=1-234 |
| 9SS4 | EM | 2.7 Å | BA=1-234 |
| 4U26 | X-ray | 2.8 Å | B5=2-229 |
| 4U27 | X-ray | 2.8 Å | B5=2-229 |
| 4U20 | X-ray | 2.9 Å | B5=2-229 |
| 4U24 | X-ray | 2.9 Å | B5=2-229 |
| 4U25 | X-ray | 2.9 Å | B5=2-229 |
| 7ST2 | EM | 2.9 Å | a=1-234 |
| 7TOS | EM | 2.9 Å | L1=3-225 |
| 4U1U | X-ray | 2.95 Å | B5=2-229 |
| 4U1V | X-ray | 3.0 Å | B5=2-229 |
| 4WOI | X-ray | 3.0 Å | B5=2-229 |
| 6WD0 | EM | 3.0 Å | a=3-225 |
| 6WDE | EM | 3.0 Å | a=3-225 |
| 9NL5 | EM | 3.0 Å | 1=6-225 |
| 8PKL | EM | 3.09 Å | a=1-234 |
| 6ENU | EM | 3.1 Å | 7=6-229 |
| 6WNT | EM | 3.1 Å | a=3-225 |
Showing 20 of 154 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.