Large ribosomal subunit protein uL23 (rplW) is a 100-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0ADZ0.
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The mean pLDDT of this model is 90.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 83% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 2% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor (PubMed:12226666) for Ffh binding to the ribosome (SRP54) (PubMed:12756233, PubMed:12702815) and to nascent polypeptide chains (PubMed:12756233)
Part of the 50S ribosomal subunit (PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:21499241, PubMed:24844575, PubMed:25310980, PubMed:27906160, PubMed:27906161, PubMed:27934701, PubMed:391594). Contacts protein L29 and trigger factor. Might also contact SecE and probably does contact SecG and SecY when the SecYEG translocation complex is docked with the ribosome (PubMed:16292303)
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8B0X | EM | 1.55 Å | s=1-100 |
| 9Q87 | EM | 1.55 Å | s=1-100 |
| 8CGK | EM | 1.64 Å | s=1-100 |
| 8CGV | EM | 1.66 Å | s=1-100 |
| 8CEU | EM | 1.83 Å | s=1-100 |
| 8FTO | EM | 1.85 Å | s=1-100 |
| 8CAM | EM | 1.86 Å | s=1-100 |
| 9GHE | EM | 1.87 Å | s=1-100 |
| 9D89 | EM | 1.95 Å | K=1-93 |
| 8AYE | EM | 1.96 Å | s=1-100 |
| 7K00 | EM | 1.98 Å | s=1-100 |
| 8CGD | EM | 1.98 Å | s=1-100 |
| 8QOA | EM | 2.0 Å | s=1-100 |
| 8G6W | EM | 2.02 Å | s=1-100 |
| 8BIL | EM | 2.04 Å | Q=1-100 |
| 8BIM | EM | 2.04 Å | Q=1-100 |
| 8G6Y | EM | 2.09 Å | s=1-100 |
| 4YBB | X-ray | 2.1 Å | CU/DU=1-93 |
| 6XZ7 | EM | 2.1 Å | T=1-93 |
| 7QQ3 | EM | 2.1 Å | b=1-100 |
Showing 20 of 577 experimental structures (best resolution first).
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