Phalloidin proprotein is a 34-residue protein from Amanita phalloides. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0CU65.
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The mean pLDDT of this model is 60.2 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 94% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Toxin that belongs to the bicyclic heptapeptides called phallotoxins (PubMed:27978833). Although structurally related to amatoxins, phallotoxins have a different mode of action, which is the stabilization of F-actin (PubMed:6452160). Phallotoxins are poisonous when administered parenterally, but not orally because of poor absorption (PubMed:27978833)
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6D8C | EM | 3.54 Å | N/O/P=10-16 |
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