P0DTD1: Replicase polyprotein 1ab

Replicase polyprotein 1ab (rep) is a 7096-residue protein from Severe acute respiratory syndrome coronavirus 2. UniProt accession: P0DTD1.

Function

Multifunctional protein involved in the transcription and replication of viral RNAs. Contains the proteinases responsible for the cleavages of the polyprotein

Subcellular location

Host cytoplasm, Host cytoplasm, Host endosome, Host endoplasmic reticulum membrane, Host endoplasmic reticulum membrane, Host cytoplasm, Host Golgi apparatus, Host nucleus, Host endoplasmic reticulum membrane, Host cytoplasm, host perinuclear region, Host cytoplasm, Host endoplasmic reticulum, Host

Subunit structure

Interacts with host GIGYF2

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Source: AlphaFold · UniProt P0DTD1