Osteopontin (SPP1) is a 314-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P10451.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 53.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 55% |
| Below 50 | Very low: often disordered regions | 40% |
What pLDDT means and how to read it
Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction
Interacts (via N-terminus) with integrin ITGA9:ITGB1
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9EOU | X-ray | 1.55 Å | P=153-168 |
| 3CXD | X-ray | 2.8 Å | P=40-51 |
| 3DSF | X-ray | 2.8 Å | P=40-51 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.