Myosin-11 (MYH11) is a 1979-residue protein from Gallus gallus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P10587.
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The mean pLDDT of this model is 76.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 21% |
| 70 to 90 | Confident: backbone generally right | 46% |
| 50 to 70 | Low: treat with caution | 29% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Muscle contraction
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2)
Cytoplasm, myofibril
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5M05 | X-ray | 2.67 Å | A=1-790 |
| 5T45 | X-ray | 2.8 Å | A=1-790 |
| 1BR2 | X-ray | 2.9 Å | A/B/C/D/E/F=2-792 |
| 7MF3 | EM | 3.4 Å | A/B/G/H=2-1979 |
| 1BR1 | X-ray | 3.5 Å | A/C/E/G=2-819 |
| 1BR4 | X-ray | 3.62 Å | A/C/E/G=2-819 |
| 6BIH | EM | 6.0 Å | H=1-790 |
| 8SYF | EM | 19.0 Å | A/B=2-851 |
| 1I84 | EM | 20.0 Å | S/V=2-1175 |
| 3DTP | EM | 20.0 Å | A/B=2-852 |
| 3J04 | EM | A/D=2-910 |
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