P14126: Large ribosomal subunit protein uL3 (RPL3)

Large ribosomal subunit protein uL3 (RPL3) is a 387-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P14126.

Gene
RPL3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
387 residues
Mean pLDDT
96.6
Model
AF-P14126-F1 v6
Model created
1 Aug 2025
PDB structures
222

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Model confidence (pLDDT)

The mean pLDDT of this model is 96.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate99%
70 to 90Confident: backbone generally right1%
50 to 70Low: treat with caution0%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:22096102, PubMed:24865971). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:22096102). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:22096102). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that…

Subunit structure

Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes). uL3 forms together with ES39L one…

Subcellular location

Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8CCSEM1.97 ÅFF=1-387
8CDREM2.04 ÅFF=1-387
8CEHEM2.05 ÅFF=1-387
8P8NEM2.15 ÅLG=1-387
8PFREM2.15 ÅLG=1-387
8EVTEM2.2 ÅAB=1-387
8T2YEM2.2 ÅAB=1-387
8P8UEM2.23 ÅLG=1-387
8CGNEM2.28 ÅFF=1-387
8ZHCEM2.3 ÅLE=2-387
7UOOEM2.34 ÅB=1-387
7V08EM2.36 ÅB=1-387
8EVPEM2.38 ÅAB=1-387
7ZW0EM2.4 ÅLF=1-387
8AGXEM2.4 Åk=1-387
8BN3EM2.4 ÅL3=2-387
8T2ZEM2.4 ÅAB=1-387
7UQBEM2.43 ÅB=1-387
7UQZEM2.44 ÅB=2-387
8EWCEM2.45 ÅAB=1-387

Showing 20 of 222 experimental structures (best resolution first).

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