Polycomb group protein Pc (Pc) is a 390-residue protein from Drosophila melanogaster. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P26017.
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The mean pLDDT of this model is 58.8 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 15% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 41% |
| Below 50 | Very low: often disordered regions | 39% |
What pLDDT means and how to read it
Polycomb group (PcG) protein (PubMed:1898775). PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (PubMed:11493925, PubMed:11583617, PubMed:1898775). PcG proteins are not required to initiate repression, but to maintain it during later stages of development (PubMed:1898775). Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility (PubMed:11493925, PubMed:11583617). Promotes locus-specific chromatin…
Component of PRC1 complex, which contains many PcG proteins like Pc, ph, Scm, Psc, Sce and also chromatin-remodeling proteins such as histone deacetylases. This complex is distinct from the Esc/E(z) complex, at least composed of esc, E(z), Su(z)12, HDAC1/Rpd3 and Caf1-55. The 2 complexes however cooperate and interact together during the first 3 hours of development to establish PcG silencing…
Nucleus, Chromosome
Compare the prediction with experimentally determined structures of the same protein:
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