ATPase family gene 2 protein (AFG2) is a 780-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P32794.
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The mean pLDDT of this model is 76.2 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 4% |
| 70 to 90 | Confident: backbone generally right | 73% |
| 50 to 70 | Low: treat with caution | 17% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes (PubMed:12006565, PubMed:17646390, PubMed:23185031, PubMed:24371142). Plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RLP24 from the pre-ribosomal particles (PubMed:17646390, PubMed:23185031, PubMed:24371142). This step facilitates the subsequent release of other shuttling proteins such as NOG1 and allows the transition of the pre-ribosomal particles to later maturation forms that bind REI1 (PubMed:17646390, PubMed:23185031, PubMed:24371142). Essential for viability…
Homohexamer; ATP binding induces oligomerization (PubMed:12006565, PubMed:23185031). Forms a ring-shaped particle of about 12 nm diameter, that displays 6-fold radial symmetry (PubMed:12006565). Associates with cytoplasmic pre-60S ribosomal particles containing ARX1, ALB1, RLP24 and NOG1 (PubMed:17646390). Binds to pre-60S ribosomal particles soon after their export from the nucleus and is…
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7Z11 | EM | 3.2 Å | A/B/C/D/E/F=1-780 |
| 7NKU | EM | 3.4 Å | A/B/C/D/E/F=1-780 |
| 7WBB | EM | 3.6 Å | A/B/C/D/E/F=1-780 |
| 7WD3 | EM | 3.8 Å | A/B/C/D/E/F=29-776 |
| 7Z34 | EM | 3.8 Å | Aa/m/n/t/w/x=1-780 |
| 7YKZ | EM | 4.3 Å | A/B/C/D/E/F=1-780 |
| 7YKL | EM | 5.6 Å | A/B/C/D/E/F=1-780 |
| 7YKK | EM | 5.9 Å | A/B/C/D/E/F=1-780 |
| 7YKT | EM | 5.9 Å | A/B/C/D/E/F=1-780 |
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