Mitochondrial import inner membrane translocase subunit TIM23 (TIM23) is a 222-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P32897.
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The mean pLDDT of this model is 72.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 33% |
| 70 to 90 | Confident: backbone generally right | 23% |
| 50 to 70 | Low: treat with caution | 26% |
| Below 50 | Very low: often disordered regions | 19% |
What pLDDT means and how to read it
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (PubMed:10548718, PubMed:40877479, PubMed:7600576, PubMed:8050570, PubMed:8354690, PubMed:9171336). TIM23 probably has a structural role rather than translocase activity (PubMed:37344598)
Component of the TIM23 complex at least composed of TIM23, TIM17, TIM50 and TIM21. The complex interacts with the TIM44 component of the PAM complex (PubMed:10548718, PubMed:15797382, PubMed:7600576, PubMed:9171336). The TIM23 complex interacts with the TOM complex to form a supercomplex (PubMed:40877479)
Mitochondrion inner membrane
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