P33298: 26S proteasome regulatory subunit 6B homolog (RPT3)

26S proteasome regulatory subunit 6B homolog (RPT3) is a 428-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P33298.

Gene: RPT3
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length: 428 residues
Mean pLDDT: 81.8
Model: AF-P33298-F1 v6
Model created: 1 Aug 2025
PDB structures: 33

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Model confidence (pLDDT)

The mean pLDDT of this model is 81.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT band	Meaning	Share of residues
Above 90	Very high: backbone and side chains are usually accurate	29%
70 to 90	Confident: backbone generally right	54%
50 to 70	Low: treat with caution	11%
Below 50	Very low: often disordered regions	6%

What pLDDT means and how to read it

Function

The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity)

Subcellular location

Cytoplasm, Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB ID	Method	Resolution	Chains and residues
2DZN	X-ray	2.2 Å	B/D/F=348-428
2DZO	X-ray	3.0 Å	B/D=348-428
9CGC	EM	3.61 Å	K=1-428
6J2Q	EM	3.8 Å	K=1-428
6J2X	EM	3.8 Å	K=1-428
5MP9	EM	4.1 Å	K=1-428
6FVT	EM	4.1 Å	K=35-428
6EF3	EM	4.17 Å	K=1-428
5WVK	EM	4.2 Å	K=1-428
6EF2	EM	4.27 Å	K=170-428
6EF0	EM	4.43 Å	K=157-428
5MPA	EM	4.5 Å	K=1-428
6FVU	EM	4.5 Å	K=35-428
6FVW	EM	4.5 Å	K=45-428
6J30	EM	4.5 Å	K=1-428
3JCP	EM	4.6 Å	K=1-428
6EF1	EM	4.73 Å	K=153-428
3JCO	EM	4.8 Å	K=1-428
6FVX	EM	4.9 Å	K=35-428
6FVV	EM	5.4 Å	K=35-428

Showing 20 of 33 experimental structures (best resolution first).

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