P33767: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 (WBP1)

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 (WBP1) is a 430-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P33767.

Gene
WBP1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
430 residues
Mean pLDDT
87.5
Model
AF-P33767-F1 v6
Model created
1 Aug 2025
PDB structures
7

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Model confidence (pLDDT)

The mean pLDDT of this model is 87.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate66%
70 to 90Confident: backbone generally right24%
50 to 70Low: treat with caution8%
Below 50Very low: often disordered regions2%

What pLDDT means and how to read it

Function

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity

Subunit structure

Component of the oligosaccharyltransferase (OST) complex, which appears to exist in two assemblies comprising OST1, OST2, OST4, OST5, STT3, SWP1, WPB1, and either OST3 or OST6 (PubMed:15831493, PubMed:15886282, PubMed:16096345, PubMed:16297388, PubMed:29301962, PubMed:8175708, PubMed:9405463). OST assembly occurs through the formation of 3 subcomplexes. Subcomplex 1 contains OST1 and OST5,…

Subcellular location

Endoplasmic reticulum membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4J86X-ray1.48 ÅC/D=425-430
8AGEEM2.8 ÅG=1-430
8AGBEM3.0 ÅG=1-430
8AGCEM3.1 ÅG=1-430
6EZNEM3.3 ÅG=1-430
7OCIEM3.46 ÅG=1-430
6C26EM3.5 ÅB=1-430

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