P34223: UBX domain-containing protein 1 (SHP1)

UBX domain-containing protein 1 (SHP1) is a 423-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P34223.

Gene
SHP1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
423 residues
Mean pLDDT
70.9
Model
AF-P34223-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 70.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate16%
70 to 90Confident: backbone generally right42%
50 to 70Low: treat with caution22%
Below 50Very low: often disordered regions20%

What pLDDT means and how to read it

Function

Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Direct or indirect positive regulator of GLC7 activity

Subunit structure

Forms a complex composed of CDC48, NPL4, UFD1, DOA1, SHP1 and deubiquitinase OTU1 (PubMed:16427015). Interacts with CDC48 (PubMed:15258615)

Subcellular location

Nucleus, Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8UB4EM2.9 ÅH/I/J=1-423
6OPCEM3.7 ÅZ=1-423

More AlphaFold highlights

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