P36519: Large ribosomal subunit protein uL5m (MRPL7)

Large ribosomal subunit protein uL5m (MRPL7) is a 292-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P36519.

Gene
MRPL7
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
292 residues
Mean pLDDT
92.9
Model
AF-P36519-F1 v6
Model created
1 Aug 2025
PDB structures
8

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Model confidence (pLDDT)

The mean pLDDT of this model is 92.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate91%
70 to 90Confident: backbone generally right2%
50 to 70Low: treat with caution2%
Below 50Very low: often disordered regions5%

What pLDDT means and how to read it

Function

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Subunit structure

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins. Unlike bacterial L5, uL5m does not bind zinc

Subcellular location

Mitochondrion

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9HM0EM3.0 ÅEE=1-292
3J6BEM3.2 ÅE=1-292
8UXAEM3.2 ÅE=19-292
9HLZEM3.2 ÅEE=1-292
5MRCEM3.25 ÅE=19-292
8UX4EM3.3 ÅE=19-292
5MREEM3.75 ÅE=19-292
5MRFEM4.97 ÅE=19-292

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